Research Article

Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification

Table 2

Characteristics of active ingredients in ABM.

No.Molecule IDMolecule nameOB (%)DL

1MOL000098Quercetin46.433348120.27525
2MOL000422Kaempferol41.882249540.24066
3MOL0003787-O-methylisomucronulatol74.686137520.29792
4MOL000392Formononetin69.673880610.21202
5MOL000354Isorhamnetin49.604377050.306
6MOL0003713,9-Di-O-methylnissolin53.741526730.47573
7MOL000296Hederagenin36.913905830.75072
8MOL000380(6aR,11aR)-9,10-dimethoxy-6a,11a-dihydro-6H-benzofurano[3,2-c]chromen-3-ol64.255454520.42486
9MOL000417Calycosin47.751827830.24278
10MOL000239Jaranol50.828816770.29148
11MOL000387Bifendate31.097823910.66553
12MOL0004421,7-Dihydroxy-3,9-dimethoxy pterocarpene39.045411120.47943
13MOL0003799,10-Dimethoxypterocarpan-3-O-β-D-glucoside36.736688010.9243
14MOL000433FA68.960436220.7057
15MOL000033(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R,5S)-5-propan-2-yloctan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol36.228470560.78288
16MOL000439Isomucronulatol-7,2-di-O-glucosiole49.281055390.62065
17MOL000211Mairin55.377073380.7761
18MOL0003745-Hydroxyiso-muronulatol-2,5-di-O-glucoside41.717665740.69251
19MOL000398Isoflavanone109.98665650.29572
20MOL000438(3R)-3-(2-hydroxy-3,4-dimethoxyphenyl)chroman-7-ol67.66747940.26479

OB, oral bioavailability; DL, drug-likeness.