Gastroenterology Research and Practice / 2022 / Article / Tab 3 / Research Article
Explore the Mechanism of Astragalus mongholicus Bunge against Nonalcoholic Fatty Liver Disease Based on Network Pharmacology and Experimental Verification Table 3 Ten key targets of ABM in treating NAFLD.
No. Gene symbol Description Degree (DC) Betweenness centrality (BC) 1 AKT1 RAC-alpha serine/threonine-protein kinase 76 0.09007483 2 IL6 Interleukin-6 75 0.06038545 3 TNF Tumor necrosis factor 72 0.04427747 4 TP53 Cellular tumor antigen p53 66 0.02811782 5 JUN Transcription factor AP-1 61 0.01848417 6 PTGS2 Prostaglandin G/H synthase 2 59 0.01631192 7 CXCL8 Interleukin-8 59 0.01898645 8 MAPK8 Mitogen-activated protein kinase 8 58 0.01679413 9 MMP9 Matrix metalloproteinase-9 57 0.02436033 10 CASP3 Caspase-3 57 0.01529514