Safety and Efficacy of Peroral Endoscopic Shorter Myotomy versus Longer Myotomy for Patients with Achalasia: A Systematic Review and Meta-analysis
Table 1
General characteristics of the studies and patients.
Study
Wang et al., 2015
Li et al., 2018
Huang et al., 2020
Gu et al., 2020
Nabi et al., 2020
Study design
Prospective cohort
Retrospective cohort
Retrospective cohort
RCT
RCT
Study period
Jan 2012 to Feb 2013
Jan 2013 to Dec 2016
Jul 2011 to Sep 2017
Feb 2018 to Feb 2019
Jun 2017 to Mar 2019
Study location
Guangzhou, China
Beijing, China
Shenzhen, China
Changsha, China
Hyderabad, India
Patients group
SM
SM
LM
SM
LM
SM
LM
SM
LM
Total patients ()
46
63
63
36
74
46
48
34
37
Mean age (years)
36
49.3
45.9
40.8
37.7
43.6
42.8
40.1
41.3
Male, (%)
17 (37)
24 (38)
30 (48)
19 (53)
40 (54)
21 (46)
23 (48)
18 (53)
24 (65)
Symptoms duration (years)
<1 year, 12; 1-5 years, 28; and >5 years, 6
9.4 (0.1-40.0)
9.4 (0.3-30.0)
0.7 (0.2-2.1)
0.7 (0.3-2.5)
5.0 (0.3-34.0)
4.1 (0.3-31.0)
3 (1.5-4.7)
3 (1.0-5.0)
Previous treatments ()
POEM, 1; PD, 7
BTI or PD or HM, 23
BTI or PD or HM, 18
BTI, 2; PD, 7
BTI, 3; PD, 9
None
None
PD, 12
PD, 9
Chicago classification, type I/type II/type III
26/19/1
16/45/2
9/52/2
12/24/0
26/48/0
0/46/0
0/48/0
12/22/0
13/24/0
Follow-up (months)
3
20.1 (6-48)
23.6 (6-48)
26.8 (8-54.3)
29.5 (6-58.8)
12
12
12
12
Continuous variables presented as mean (SD) or Median (IQR). SM: short myotomy; LM: long myotomy; POEM: peroral endoscopic myotomy; PD: pneumatic dilatation; BTI: botulinum toxin injection; SD: standard deviation; IQR: interquartile range.
