Research Article

Standardization and Quality Control of the Herbal Medicine Mist Nibima, Employed to Treat Malaria and COVID-19, Using Physicochemical and Organoleptic Parameters and Quantification of Chemical Markers via UHPLC-MS/MS

Table 5

Names of compounds/active ingredients identified in Mist Nibima and their RTs, peak areas, percentage compositions, and concentrations in Mist Nibima.

PeakProposed compoundRT (min)AreaComposition in Mist Nibima (%) (µg/mL) (mg/330 mL bottle)

1Quindoline1.3522070555301.320.7810.42 ± 0.1433.44 ± 0.047
2Methyl cryptolepinoate1.5773697465123.337.1018.64 ± 0.2556.15 ± 0.084
3Hydroxycryptolepine6.321339811726.263.411.70 ± 0.0230.56 ± 0.011
4Cryptolepine9.8353344237823.933.5616.85 ± 0.2315.56 ± 0.076
511-Isopropylcryptolepine10.962514102921.065.162.56 ± 0.0340.85 ± 0.007