Quantitative Analysis of Favipiravir by HPLC: Development and Validation

Table 1

Solutions for forced degradation studies under stressful conditions.

#	Sample solution conc. (mg/ml)	Sample weight (mg)	Stress condition	Total volume (ml)
1	0.5	225	—	200
2	0.5	225	0.5 M NaOH & heat in water bath @ 50°C, 15 minutes	200
3	0.5	225	0.5 M HCl & heat in water bath @ 70°C, 15 minutes	200
4	0.5	225	6% H2O2 & heat in water bath @ 70°C, 15 minutes	200
5	0.5	225	Heat in water bath @ 70°C, 15 minutes	200
6	0.5	225	Under UV light for 24 hrs	200