Research Article
Quantitative Analysis of Favipiravir by HPLC: Development and Validation
Table 12
Filter absorbance results according to volume.
| Sample no | 100% of nominal standard | 100% of nominal spiked sample | Filtrated total volume (ml) | Area | Recovery (%) | Filtrated total volume (ml) | Area | Recovery (%) |
| 1 | 1 | 34.593 | 95.1 | 1 | 34.055 | 93.7 | 2 | 2 | 35.34 | 97.2 | 2 | 34.837 | 95.8 | 3 | 3 | 36.429 | 100.2 | 3 | 35.938 | 98.8 | 4 | 4 | 36.426 | 100.2 | 4 | 35.896 | 98.7 | 5 | 5 | 36.405 | 100.1 | 5 | 35.902 | 98.7 | 6 | 6 | 36.421 | 100.2 | 6 | 35.887 | 98.7 | Average | 35.8386 | | | | |
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Determine the saturation point that achieves recovery value at least within 98%–102% after 3 ml according to the results.
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