Analytical and Clinical Evaluation of a Chemiluminescent Immunoassay to Detect Serum Chitinase-3-like Protein 1 in HBV-Related Liver Diseases

Table 2

Immunoassay methods to detect serum CHI3L1 levels.

Methods	ELISA	MB-FIA	FICA	CLIA
Time (min)	>120	>20	>20	>20
Detection range (ng/mL)	60.35–969.98	2.90–111.00	5.00–200.00	0.98–2000.00
LOD (ng/mL)	60.35	2.90	5.00	0.98
Reference	2016 [10]	2015 [11]	2021 [12]	Present study

ELISA, enzyme-linked immunosorbent assay; MB-FIA, magnetic bead fluorescent immunoassay; FICA, fluorescence immunochromatography assay; CLIA, chemiluminescence immunoassay; LOD, limit of detection; CHI3L1, chitinase-3-like protein 1.