Pharmacokinetics of Ziyuglycoside I and Ziyuglycoside II in Rat Plasma by UPLC-MS/MS

Table 1

Accuracy, precision, matrix effect, and recovery of ziyuglycoside I and ziyuglycoside II in rat plasma.

Compound	Concentration (ng/mL)	Accuracy (%)		Precision (RSD%)		Matrix effect (%)	Recovery (%)
		Intra-day	Inter-day	Intra-day	Inter-day
Ziyuglycoside I	2	89.7	108.6	10.2	7.7	109.6	84.6
	8	101.9	99.8	8.9	10.9	88.4	89.0
	150	96.0	104.6	9.2	4.8	112.5	88.1
	1500	98.0	97.0	4.2	4.8	109.7	94.4
Ziyuglycoside II	2	87.9	106.8	14.1	13.6	95.5	92.0
	8	100.9	98.4	5.9	9.0	98.2	89.0
	150	109.9	106.2	8.3	10.5	88.4	90.1
	1500	106.7	97.7	9.7	1.4	96.8	88.9