In Silico Investigation of Novel Compounds as Inhibitors of Acetylcholinesterase Enzyme for the Treatment of Alzheimer’s Diseases

Figure 4

Interaction of Zoladex within the binding site of AChE shows interaction with the amino acids in the choline binding site TYR-70. Asp 72 in the acyl binding site and pi-pi interaction with the TRP-279 and LEU 282 around the peripheral anionic binding site.

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