In Silico Investigation of Novel Compounds as Inhibitors of Acetylcholinesterase Enzyme for the Treatment of Alzheimer’s Diseases

Table 3

Toxicity results of the four compounds obtained from ProTox-II online tools.

S/no.	Compound	Mutagenicity	Hepatoxicity	Carcinogenicity	Immunotoxicity	Cytotoxicity	Predicted LD50 (mg/kg)	Predicted toxicity
1	Donepezil	Inactive	Inactive	Inactive	Active	Moderately active	505	4
2	Galantamine	Inactive	Inactive	Moderately inactive	Active	Moderately active	85	3
3	Zoladex	Moderately inactive	Inactive	Moderately inactive	Inactive	Moderately inactive	2400	5
4	CHEMBL-1240685	Moderately inactive	Inactive	Moderately inactive	Inactive	Inactive	3000	5