|
| Protein orthologues | Expression alteration ratio in B. pseudomallei strains | pI | MW | Spot number |
| Wild type | rpoN2 mutant |
|
| (1) Cell envelope biogenesis and outer membrane | | | | | |
| Acetyltransferase (GNAT) family protein | 1 | ↑ 8.30 | 4.9 | 50.17 | 9 |
| UDP-N-acetylmuramyl pentapeptide synthase | 1 | ↑ 5.02 | 5.7 | 41.55 | 2 |
| (2) Energy metabolism | | | | | |
| Polyphosphate kinase 2 family (Ppk2) | 1 | ↑ 3.17 | 4.89 | 44.26 | 40 |
| ATB synthase subunit B | 1 | ↑ 3.40 | 4.97 | 53.93 | 15 |
| NADH-dehydrogenase delta subunit | 1 | 0.17 ↓ | 5.34 | 36.59 | 26 |
| Aldehyde dehydrogenase (NAD) family protein | 1 | 0.19 ↓ | 6.02 | 55.39 | 24 |
| (3) Carbohydrate metabolism | | | | | |
| Glyceraldehyde 3-phosphate dehydrogenase (GapA) | 1 | ↑ 3.38 | 4.82 | 20.88 | 48 |
| Nucleoside-diphosphate-sugar epimerases | 1 | ↑ 12.58 | 5.21 | 27.78 | 56 |
| (4) Lipid metabolism | | | | | |
| 4-Hydroxyl-3-methylbut-2-enyl diphosphate reductase (lspH) | 1 | ↑ 5.07 | 5.94 | 40.81 | 71 |
| Nonribosomally encoded peptide/polyketide synthase (CmaB) | 1 | 0.21 ↓ | 6.19 | 37.19 | 73 |
| (5) Amino acid metabolism | | | | | |
| Phosphoribosyl formimino-5-aminoimidazole carboxamide ribotide isomerase (HisA) | 1 | 0.20 ↓ | 4.42 | 31 | 83 |
| Cysteine synthase (CysM) | 1 | 0.33 ↓ | 5.75 | 36.11 | 80 |
| (6) Nucleotide metabolism | | | | | |
| Orotidine 5′-phosphate decarboxylase | 1 | ↑ 6.42 | 4.99 | 32.79 | 88 |
| (7) Translation | | | | | |
| 50S ribosomal protein L3 | 1 | ↑ 3.49 | 4.14 | 27.8 | 150 |
| (8) Transcription | | | | | |
| Transcriptional regulator, ArsR family 1 | 1 | 0.20 ↓ | 4.92 | 37.92 | 124 |
| (9) Posttranslational modification | | | | | |
| Thioredoxin | 1 | ↑ 3.37 | 5.97 | 16.15 | 179 |
| Peptidyl-prolyl cis-trans isomerase B | 1 | ↑ 22.15 | 6.05 | 19.99 | 174 |
| Glutathione S-transferase | 1 | ↑ 3.05 | 6.5 | 22 | 176 |
| (10) Cell motility, intracellular trafficking, and secretion | | | | | |
| Type III effector protein BipD | 1 | ↑ 5.04 | 4.38 | 34.37 | 194 |
| Type III secretion chaperone LcrH/SycD | 1 | ↑ 6.23 | 4.92 | 18.52 | 190 |
| (11) Stress responses | | | | | |
| Carbohydrate porin, OprB family | 1 | ↑ 3.16 | 5.01 | 38.71 | 233 |
| (12) Hypothetical protein | | | | | |
| Hypothetical protein BPSL0349 | 1 | ↑ 3.15 | 5.28 | 16.53 | 253 |
| Hypothetical protein BPSS0931 | 1 | 0.03 ↓ | 4.64 | 23.63 | 274 |
|
