International Journal of Chemical Engineering / 2024 / Article / Tab 3 / Research Article
A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method Table 3 Dissolution test of design batches.
Time (min) Percentage drug release (%) 10 44.88 ± 1.23 51.82 ± 0.98 61.09 ± 2.56 52.52 ± 1.85 61.98 ± 1.97 65.00 ± 0.68 63.22 ± 2.85 73.82 ± 2.16 74.95 ± 1.66 20 59.94 ± 1.56 62.32 ± 2.71 74.01 ± 1.68 65.32 ± 1.45 76.06 ± 0.68 79.35 ± 1.06 75.49 ± 2.74 81.98 ± 0.86 83.71 ± 1.52 30 73.25 ± 2.14 79.82 ± 1.85 83.57 ± 1.35 79.34 ± 2.01 83.64 ± 1.32 82.98 ± 1.89 86.57 ± 1.73 90.24 ± 1.83 90.25 ± 2.11 60 91.46 ± 1.61 93.51 ± 2.54 90.84 ± 1.98 91.25 ± 0.98 95.99 ± 2.29 94.52 ± 2.16 98.67 ± 2.84 99.03 ± 2.61 101.77 ± 1.26