The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers

<table>Synthesis of <i>N</i>-arachidonoylethanolamine (AEA). <i>N</i>-acyltransferase (NAT) catalyzes the transfer of arachidonic acid (AA) from phosphatidylcholine (PC) to phosphatidylethanolamine (PE) to form <i>N</i>-arachidonoyl-phosphatidylethanolamine (NAPE). NAPE is then converted into AEA in a one-step hydrolysis reaction catalyzed by the NAPE-specific phospholipase D (NAPE-PLD).</table>

International Journal of Endocrinology

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Figure 1

Figure 1: The Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers 