Research Article
Obesity and Insulin Resistance Are the Main Determinants of Postprandial Lipoprotein Dysmetabolism in Polycystic Ovary Syndrome
Table 5
Postprandial TG, HDL, apoB-48, glucose, and insulin levels adjusted for BMI,
, and
.
| | Covariate: BMI | Covariate: HOMAIR | Covariate: | | PCOS | Controls | PCOS | Controls | PCOS | Controls |
| TG 0 hrs (mmol/L) | 1.54 ± 0.13 | 1.25 ± 0.12 | 1.40 ± 0.11 | 1.36 ± 0.11 | 1.47 ± 0.13 | 1.33 ± 0.14 | TG 2 hrs (mmol/L) | 2.14 ± 0.16 | 1.66 ± 0.16 | 1.97 ± 0.14 | 1.79 ± 0.14 | 2.04 ± 0.17 | 1.73 ± 0.18 | TG 4 hrs (mmol/L) | 2.37 ± 0.20 | 1.90 ± 0.19 | 2.14 ± 0.16 | 2.10 ± 0.16 | 2.24 ± 0.20 | 2.10 ± 0.22 | TG 6 hrs (mmol/L) | 1.92 ± 0.21 | 1.57 ± 0.21 | 1.70 ± 0.18 | 1.75 ± 0.18 | 1.80 ± 0.22 | 1.77 ± 0.24 | TG 8 hrs (mmol/L) | 1.71 ± 0.19 | 1.37 ± 0.19 | 1.48 ± 0.16 | 1.56 ± 0.16 | 1.60 ± 0.20 | 1.56 ± 0.22 | AUC-TG (mmol/L⋅8 hrs) | 8.06 ± 0.68 | 6.45 ± 0.66 | 7.25 ± 0.54 | 7.10 ± 0.54 | 7.61 ± 0.70 | 7.04 ± 0.76 | iAUC-TG (mmol/L⋅8 hrs) | 1.87 ± 0.29 | 1.45 ± 0.29 | 1.63 ± 0.27 | 1.65 ± 0.27 | 1.64 ± 0.31 | 1.82 ± 0.33 | HDL-chol 0 hrs (mmol/L) | 1.40 ± 0.06 | 1.45 ± 0.06 | 1.41 ± 0.06 | 1.44 ± 0.06 | 1.40 ± 0.06 | 1.38 ± 0.07 | HDL-chol 2 hrs (mmol/L) | 1.33 ± 0.06 | 1.38 ± 0.06 | 1.34 ± 0.05 | 1.37 ± 0.05 | 1.34 ± 0.06 | 1.33 ± 0.07 | HDL-chol 4 hrs (mmol/L) | 1.27 ± 0.06 | 1.32 ± 0.05 | 1.28 ± 0.05 | 1.31 ± 0.05 | 1.28 ± 0.06 | 1.27 ± 0.06 | HDL-chol 6 hrs (mmol/L) | 1.30 ± 0.06 | 1.37 ± 0.06 | 1.32 ± 0.06 | 1.36 ± 0.06 | 1.31 ± 0.06 | 1.31 ± 0.07 | HDL-chol 8 hrs (mmol/L) | 1.35 ± 0.06 | 1.38 ± 0.06 | 1.36 ± 0.06 | 1.37 ± 0.06 | 1.36 ± 0.06 | 1.32 ± 0.07 | AUC-HDL-chol (mmol/L⋅8 hrs) | 5.28 ± 0.23 | 5.49 ± 0.22 | 5.33 ± 0.22 | 5.44 ± 0.22 | 5.31 ± 0.24 | 5.26 ± 0.26 | iAUC-HDL-chol (mmol/L⋅8 hrs) | −0.33 ± 0.06 | −0.31 ± 0.06 | −0.33 ± 0.06 | −0.32 ± 0.06 | −0.30 ± 0.06 | −0.27 ± 0.07 | ApoB-48 0 hrs (μg/mL) | 12.4 ± 1.54 | 9.70 ± 1.47 | 11.9 ± 1.49 | 9.86 ± 1.46 | 11.9 ± 1.70 | 10.4 ± 1.80 | ApoB-48 2 hrs (μg/mL) | 17.3 ± 1.43 | 15.6 ± 1.36 | 17.0 ± 1.37 | 15.7 ± 1.34 | 16.5 ± 1.53 | 16.9 ± 1.62 | ApoB-48 4 hrs (μg/mL) | 19.6 ± 1.77 | 15.5 ± 1.69 | 19.8 ± 1.68 | 15.2 ± 1.64 | 19.2 ± 1.90 | 16.8 ± 2.00 | ApoB-48 6 hrs (μg/mL) | 18.9 ± 2.06 | 15.6 ± 1.97 | 17.2 ± 1.94 | 16.9 ± 1.90 | 17.9 ± 2.22 | 17.5 ± 2.34 | ApoB-48 8 hrs (μg/mL) | 13.2 ± 1.60 | 11.2 ± 1.53 | 11.7 ± 1.47 | 12.4 ± 1.44 | 12.3 ± 1.70 | 12.5 ± 1.79 | Log ApoB-48 (μg/mL⋅8 hrs) | 67.8 ± 5.51 | 57.1 ± 5.26 | 65.6 ± 5.30 | 58.4 ± 5.18 | 65.0 ± 5.97 | 62.5 ± 6.30 | iAUC apoB-48 (μg/mL⋅8 hrs) | 19.02 ± 3.33 | 18.31 ± 3.18 | 17.57 ± 3.19 | 19.98 ± 3.12 | 17.92 ± 3.70 | 21.06 ± 3.91 | Insulin 0 hrs (pmol/L) | 17.9 ± 1.56 | 13.4 ± 1.2 | 15.4 ± 0.30 | 15.6 ± 0.30 | 17.5 ± 1.66 | 15.1 ± 1.79 | Insulin 2 hrs (pmol/L) | 95.7 ± 10.3 | 59.5 ± 10.1 | 88.7 ± 8.91 | 63.8 ± 8.91 | 91.6 ± 11.3 | 64.1 ± 12.2 | Insulin 4 hrs (pmol/L) | 47.6 ± 5.59 | 24.6 ± 5.47 | 43.7 ± 4.92 | 27.6 ± 4.92 | 45.7 ± 5.94 | 27.7 ± 6.42 | Insulin 6 hrs (pmol/L) | 20.9 ± 1.90 | 11.6 ± 1.86 | 19.2 ± 1.57 | 12.9 ± 1.57 | 19.9 ± 1.94 | 13.2 ± 2.11 | Insulin 8 hrs (pmol/L) | 13.6 ± 1.89 | 14.4 ± 1.84 | 13.4 ± 1.81 | 14.3 ± 1.81 | 14.1 ± 2.17 | 14.7 ± 2.35 | AUC-insulin (pmol/L⋅8 hrs) | 180 ± 16.2 | 110 ± 15.8 | 166 ± 13.0 | 119 ± 13.0 | 173 ± 17.5 | 120 ± 18.9 | iAUC-insulin (pmol/L⋅8 hrs) | 108 ± 13.5 | 55.9 ± 13.2 | 104 ± 13.0 | 57.0 ± 13.0 | 103 ± 14.7 | 59.6 ± 15.9 |
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ANCOVA analysis after log transformation. versus controls. versus controls.
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