Research Article

Obesity and Insulin Resistance Are the Main Determinants of Postprandial Lipoprotein Dysmetabolism in Polycystic Ovary Syndrome

Table 5

Postprandial TG, HDL, apoB-48, glucose, and insulin levels adjusted for BMI, , and .

Covariate: BMICovariate: HOMAIRCovariate:
PCOSControlsPCOSControlsPCOSControls

TG 0 hrs (mmol/L)1.54 ± 0.131.25 ± 0.121.40 ± 0.111.36 ± 0.111.47 ± 0.131.33 ± 0.14
TG 2 hrs (mmol/L)2.14 ± 0.161.66 ± 0.161.97 ± 0.141.79 ± 0.142.04 ± 0.171.73 ± 0.18
TG 4 hrs (mmol/L)2.37 ± 0.201.90 ± 0.192.14 ± 0.162.10 ± 0.162.24 ± 0.202.10 ± 0.22
TG 6 hrs (mmol/L)1.92 ± 0.211.57 ± 0.211.70 ± 0.181.75 ± 0.181.80 ± 0.221.77 ± 0.24
TG 8 hrs (mmol/L)1.71 ± 0.191.37 ± 0.191.48 ± 0.161.56 ± 0.161.60 ± 0.201.56 ± 0.22
AUC-TG (mmol/L⋅8 hrs)8.06 ± 0.686.45 ± 0.667.25 ± 0.547.10 ± 0.547.61 ± 0.707.04 ± 0.76
iAUC-TG (mmol/L⋅8 hrs)1.87 ± 0.291.45 ± 0.291.63 ± 0.271.65 ± 0.271.64 ± 0.311.82 ± 0.33
HDL-chol 0 hrs (mmol/L)1.40 ± 0.061.45 ± 0.061.41 ± 0.061.44 ± 0.061.40 ± 0.061.38 ± 0.07
HDL-chol 2 hrs (mmol/L)1.33 ± 0.061.38 ± 0.061.34 ± 0.051.37 ± 0.051.34 ± 0.061.33 ± 0.07
HDL-chol 4 hrs (mmol/L)1.27 ± 0.061.32 ± 0.051.28 ± 0.051.31 ± 0.051.28 ± 0.061.27 ± 0.06
HDL-chol 6 hrs (mmol/L)1.30 ± 0.061.37 ± 0.061.32 ± 0.061.36 ± 0.061.31 ± 0.061.31 ± 0.07
HDL-chol 8 hrs (mmol/L)1.35 ± 0.061.38 ± 0.061.36 ± 0.061.37 ± 0.061.36 ± 0.061.32 ± 0.07
AUC-HDL-chol (mmol/L⋅8 hrs)5.28 ± 0.235.49 ± 0.225.33 ± 0.225.44 ± 0.225.31 ± 0.245.26 ± 0.26
iAUC-HDL-chol (mmol/L⋅8 hrs)−0.33 ± 0.06−0.31 ± 0.06−0.33 ± 0.06−0.32 ± 0.06−0.30 ± 0.06−0.27 ± 0.07
ApoB-48 0 hrs (μg/mL)12.4 ± 1.549.70 ± 1.4711.9 ± 1.499.86 ± 1.4611.9 ± 1.7010.4 ± 1.80
ApoB-48 2 hrs (μg/mL)17.3 ± 1.4315.6 ± 1.3617.0 ± 1.3715.7 ± 1.3416.5 ± 1.5316.9 ± 1.62
ApoB-48 4 hrs (μg/mL)19.6 ± 1.7715.5 ± 1.6919.8 ± 1.6815.2 ± 1.6419.2 ± 1.9016.8 ± 2.00
ApoB-48 6 hrs (μg/mL)18.9 ± 2.0615.6 ± 1.9717.2 ± 1.9416.9 ± 1.9017.9 ± 2.2217.5 ± 2.34
ApoB-48 8 hrs (μg/mL)13.2 ± 1.6011.2 ± 1.5311.7 ± 1.4712.4 ± 1.4412.3 ± 1.7012.5 ± 1.79
Log ApoB-48 (μg/mL⋅8 hrs)67.8 ± 5.5157.1 ± 5.2665.6 ± 5.3058.4 ± 5.1865.0 ± 5.9762.5 ± 6.30
iAUC apoB-48 (μg/mL⋅8 hrs)19.02 ± 3.3318.31 ± 3.1817.57 ± 3.1919.98 ± 3.1217.92 ± 3.7021.06 ± 3.91
Insulin 0 hrs (pmol/L)17.9 ± 1.5613.4 ± 1.215.4 ± 0.3015.6 ± 0.3017.5 ± 1.6615.1 ± 1.79
Insulin 2 hrs (pmol/L)95.7 ± 10.359.5 ± 10.188.7 ± 8.9163.8 ± 8.9191.6 ± 11.364.1 ± 12.2
Insulin 4 hrs (pmol/L)47.6 ± 5.5924.6 ± 5.4743.7 ± 4.9227.6 ± 4.9245.7 ± 5.9427.7 ± 6.42
Insulin 6 hrs (pmol/L)20.9 ± 1.9011.6 ± 1.8619.2 ± 1.5712.9 ± 1.5719.9 ± 1.9413.2 ± 2.11
Insulin 8 hrs (pmol/L)13.6 ± 1.8914.4 ± 1.8413.4 ± 1.8114.3 ± 1.8114.1 ± 2.1714.7 ± 2.35
AUC-insulin (pmol/L⋅8 hrs)180 ± 16.2110 ± 15.8166 ± 13.0119 ± 13.0173 ± 17.5120 ± 18.9
iAUC-insulin (pmol/L⋅8 hrs)108 ± 13.555.9 ± 13.2104 ± 13.057.0 ± 13.0103 ± 14.759.6 ± 15.9

ANCOVA analysis after log transformation. versus controls. versus controls.