Sex Differences in the Effect of Type 2 Diabetes on Major Cardiovascular Diseases: Results from a Population-Based Study in Italy
Table 2
N of events, person-years, and age-adjusted event rates (AAER) per 10,000 person-years and incidence rate ratios (IRR) with 95% confidence intervals (95% CI) by sex and type of event.
Events
Men
Women
Without T2D
With T2D
Without T2D
With T2D
N of events (fatal)
Person-years
AAER
N of events (fatal)
Person-years
AAER
IRR (95% CI)
N of events (fatal)
Person-years
AAER
N of events (fatal)
Person-years
AAER
IRR (95% CI)
Stroke
1454 (95)
475,145.4
37.28
517 (36)
38,600.9
74.70
1.86 (1.68–2.06)
1301 (115)
506,105.0
30.10
341 (22)
30,187.2
61.73
1.81 (1.61–2.04)
Myocardial infarction
1590 (217)
474,943.0
39.04
459 (60)
38,716.2
78.02
1.78 (1.60–2.00)
713 (128)
506,799.3
16.13
241 (37)
30,328.7
47.58
2.58 (2.22–3.00)
Heart failure
816 (14)
475,993.8
21.47
481 (10)
38,702.4
63.71
2.78 (2.48–3.12)
718 (17)
506,803.8
17.10
306 (10)
30,262.9
48.83
2.59 (2.27–2.97)
Age-adjusted event rates were calculated using Italian population at December 31st, 2011, stratified by sex. IRR = calculated using Poisson model, adjusted for age and foreign status. People without type 2 diabetes were used as reference.
