|
| S. no. | Entry no. | Protein name | Essential enzyme |
|
| 1. | Rv1820 | Acetolactate synthase | Yes |
| 2. | Rv0951 | Succinyl-CoA synthetase subunit beta | Yes |
| 3. | Rv2987c | Isopropylmalate isomerase small subunit | Yes |
| 4. | Rv1475c | Aconitate hydratase (EC: 4.2.1.3) | Yes |
| 5. | Rv0066c | Isocitrate dehydrogenase (EC: 1.1.1.42) | Yes |
| 6. | Rv2454c | 2-Oxoglutarate ferredoxin oxidoreductase subunit beta (EC: 1.2.7.3) | Yes |
| 7. | Rv1240 | Malate dehydrogenase (EC: 1.1.1.37) | Yes |
| 8. | Rv1098c | Fumarate hydratase (EC: 4.2.1.2) | Yes |
| 9. | Rv0247c | Fumarate reductase iron-sulfur subunit (EC: 1.3.99.1) | Yes |
| 10. | Rv3356c | Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate Cyclohydrolase (EC: 1.5.1.5 3.5.4.9) | Yes |
| 11. | Rv0951 | Succinyl-CoA synthetase subunit beta (EC: 6.2.1.5) | Yes |
| 12. | Rv0904c | Putative acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (EC: 6.4.1.2) | Yes |
| 13. | Rv0973c | Acetyl-/propionyl-coenzyme A carboxylase subunit alpha (EC: 6.3.4.14) | Yes |
| 14. | Rv1492 | Methylmalonyl-CoA mutase small subunit (EC: 5.4.99.2) | Yes |
| 15. | Rv3667 | Acetyl-CoA synthetase (EC: 6.2.1.1) | Yes |
| 16. | Rv0409 | Acetate kinase (EC: 2.7.2.1) | Yes |
| 17. | Rv0408 | Phosphate acetyltransferase (EC: 2.3.1.8) | Yes |
| 18. | Rv0243 | Acetyl-CoA acetyltransferase (EC: 2.3.1.9) | Yes |
| 19. | Rv0860 | Fatty oxidation protein FadB | Yes |
| 20. | Rv3667 | Acetyl-CoA synthetase (EC: 6.2.1.1) | Yes |
| 21. | Rv0373c | Carbon monoxyde dehydrogenase large subunit (EC: 1.2.99.2) | No |
| 22. | Rv2900c | Formate dehydrogenase H (EC: 1.2.1.2) | No |
| 23. | Rv1023 | Phosphopyruvate hydratase (EC: 4.2.1.11) | Yes |
| 24. | Rv1240 | Malate dehydrogenase (EC: 1.1.1.37) | Yes |
| 25. | Rv0070c | Serine hydroxymethyltransferase (EC: 2.1.2.1) | Yes |
| 26. | Rv2205c | Hypothetical protein | Yes |
| 27. | Rv0761c | Zinc-containing alcohol dehydrogenase NAD dependent AdhB (EC: 1.1.1.1) | Yes |
| 28. | Rv0489 | Phosphoglyceromutase (EC: 5.4.2.1) | Yes |
| 29. | Rv0363c | Fructose-bisphosphate aldolase (EC: 4.1.2.13) | Yes |
| 30. | Rv2029c | Phosphofructokinase PfkB (phosphohexokinase) (EC: 2.7.1.—) | Yes |
| 31. | Rv1908c | Catalase-peroxidase-peroxynitritase T KatG (EC: 1.11.1.6) | Yes |
| 32. | Rv0070c | Serine hydroxymethyltransferase (EC: 2.1.2.1) | Yes |
| 33. | Rv0728c | D-3-phosphoglycerate dehydrogenase (EC: 1.1.1.95) | Yes |
| 34. | Rv0505c | Phosphoserine phosphatase (EC: 3.1.3.3) | Yes |
| 35. | Rv0884c | Phosphoserine aminotransferase (EC: 2.6.1.52) | Yes |
| 36. | Rv0409 | Acetate kinase (EC: 2.7.2.1) | Yes |
| 37. | Rv0408 | Phosphate acetyltransferase (EC: 2.3.1.8) | Yes |
| 38. | Rv3667 | Acetyl-CoA synthetase (EC: 6.2.1.1) | Yes |
| 39. | Rv2611c | Lipid A biosynthesis lauroyl acyltransferase (EC: 2.3.1. —) | Yes |
| 40. | Rv0114 | D-alpha,beta-D-heptose-1,7-biphosphate phosphatase (EC: 2. —.—.—) | Yes |
| 41. | Rv0113 | Phosphoheptose isomerase (EC: 5. —.—.—) | Yes |
| 42. | Rv1315 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC: 2.5.1.7) | Yes |
| 43. | Rv0482 | UDP-N-acetylenolpyruvoylglucosamine reductase (EC: 1.1.1.158) | Yes |
| 44. | Rv2152c | UDP-N-acetylmuramate-L-alanine ligase (EC: 6.3.2.8) | Yes |
| 45. | Rv2155c | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase (EC: 6.3.2.9) | Yes |
| 46. | Rv2157c | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF | Yes |
| 47. | Rv2156c | Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC: 2.7.8.13) | Yes |
| 48. | Rv2153c | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase (EC: 2.4.1.227) | Yes |
| 49. | Rv2911 | D-alanyl-D-alanine carboxypeptidase (EC: 3.4.16.4) | No |
| 50. | Rv2981c | D-alanyl-alanine synthetase A (EC: 6.3.2.4) | Yes |
| 51. | Rv2136c | Undecaprenyl pyrophosphate phosphatase (EC: 3.6.1.27) | Yes |
| 52. | Rv2911 | D-alanyl-D-alanine carboxypeptidase (EC: 3.4.16.4) | No |
| 53. | Rv2158c | UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (EC: 6.3.2.13) | Yes |
| 54. | Rv2157c | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF | Yes |
| 55. | Rv2156c | Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC: 2.7.8.13) | Yes |
| 56. | Rv2153c | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase (EC: 2.4.1.227) | Yes |
| 57. | Rv3910 | Transmembrane protein | Yes |
| 58. | Rv0016c | Penicillin-binding protein PbpA | Yes |
| 59. | Rv2163c | Penicillin-binding membrane protein PbpB | Yes |
| 60. | Rv2911 | D-alanyl-D-alanine carboxypeptidase (EC: 3.4.16.4) | No |
|
