Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes

Figure 2

Phylogenetic tree of Hop1/ASY1-similar proteins found in the proteomes of unicellular eukaryotes. The initial set of proteins used to construct the fast minimum evolution tree included RefSeq: NP_012193.1, SC protein Hop1 (Saccharomyces cerevisiae, Ascomycota); RefSeq: NP_564896.1, SC protein ASY1 (Arabidopsis thaliana, Euphyllophyta); RefSeq: XP_001321336 (Trichomonas vaginalis, Parabasalia); RefSeq: XP_002675215 (Naegleria gruberi, Heterolobosea); GenBank: EET02094, annotated as Hop1 homolog (Giardia intestinalis, Fornicata); RefSeq: XP_626119 (Cryptosporidium parvum, Apicomplexa); GenBank: CCC51501 (Trypanosoma vivax, Euglenozoa); RefSeq: XP_001742099 (Monosiga brevicollis, Choanoflagellata). The archaeal protein RefSeq: YP_003707339.1 (Methanococcus voltae, Archaea) was taken as control. Only species and higher taxa are indicated on tree. Two proteins (from Archaea and Choanoflagellata) were automatically removed from the final version of the tree. The evolutionary distance between two sequences was modeled as expected fraction of amino acid substitutions per site given the fraction of mismatched amino acids in the aligned region (according to [43]).