Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes

Table 5

SC proteins with similarities to proteins from the proteomes of multicellular eukaryotes.

Eukaryotic taxa	Total proteins in the NCBI database^a	Proteins of the SC central space		Lateral element proteins and other SC proteins
		1	2	3	4
		From animals	From plants and fungi	From plants and fungi	From animals
Porifera and Placozoa (sponges, placozoans, and Metazoa)	16445	SYP-1 Ce (56)c,; C(3)G Dm (70)c,; SYCP1 Dr (66)c,; SYCP1 Mm (88)c	ZYP1a At (83)c,; ZYP1b At (64)c,; Zip1 Sc (72)c	ASY2 At (76),; ASY1 At (137),; Hop1 Sc (71)	HIM-3 Ce (56), SC65 Dr (102), SC65 Mm (110), SYCP3-like Dr (112), SYCP3 Mm (116), FKBP6 Mm (208), SCP3(SYCP3)-like annotated for Amphimedon queenslandica
Coelenterates: Cnidaria (stingers), Ctenophora (sea walnuts), and Eumetazoa	81390	SYCE2 Dr (52),; SYCE2 Mm (63)	Low similarity	ASY2 At (78),; ASY1 At (137),; Hop1 Sc (82)	HIM-3 Ce (68), SC65 Mm (100), SC65 Dr (105), SYCP3-like Dr (143), SYCP3 Mm (148), FKBP6 Mm (194), SYCP3-like annotated for Hydra magnipapillata
Platyhelminthes (flat worms, Eumetazoa, Bilateria, and Acoelomata)	81455	SYCP1 Mm (53)	Low similarity	ASY1 At (105),; ASY2 At (62),; Hop1 Sc (57)	HIM-3 Ce (68), SYCP2 Mm (53),; FKBP6 Mm (138)
Nematoda (round worms, Bilateria, Coelomata, and Protostomia)	297231	C(3)G Dm (50),; SYCP1 Dr (51),; SYCP1 Mm (50)^b	ZYP1a At (52),; Zip1 Sc (50)	Hop1 Sc (75),; ASY2 At (86),; ASY1 At (124)	SC65 Dr (123), SC65 Mm (130), FKBP6 Mm (77), SC65 annotated for Ascaris suum and HIM-3, for several Caenorhabditis species (maximal score = 43)^b
Mollusca (Protostomia)	121831	C(3)G Dm (68)c,; SYP-1 Ce (68)c,; SYCP1 Dr (64)c,; SYCP1 Mm (99)c,; SYCE2 Mm (51)	ZYP1b At (71)c,; ZYP1a At (81)c,; Zip1 Sc (77)c	ASY1 At (89),; Hop1 Sc (55)	SC65 Dr (57), SYCP3-like Dr (199),; SC65 Mm (66), SYCP2 Mm (80),; FKBP6 Mm (171), SYCP3 Mm (197),; SYCP2 and SYCP3 annotated for Crassostrea gigas
Chelicerata (Panarthropoda 2 and Protostomia)	125005	Low similarity	Low similarity	Low similarity	SC65 Dr (88), SC65 Mm (99), FKBP6 Mm (179)
Mandibulata (Panarthropoda 3 and Protostomia)	1624768	Low similarity apart from cognate proteins^b	Low similarity	ASY1 At (63),; Hop1 Sp (55),; Hop1 Sc (60)	SC65 Dr (143), FKBP6 Mm (156),; SC65 Mm (169)b

aAs of the time of study (October 2012–April 2013).
^bSimilarity with cognate proteins is not shown.
^cThese scores (with 𝐸-values ranging from 3𝑒⁻¹⁰ to 2𝑒⁻²⁰) approximate the scores obtained for the random analogs of the SC proteins (𝐸-values ranging from 2𝑒⁻⁰⁴ to 1𝑒⁻¹¹) (italicized).
Other designations are as in Table 3.