Review Article

Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic-Based Approach for the Treatment of Hypertension in Africans

Table 1

The top five causes of death in Africa recorded in 2019 by the World Health Organisation (WHO).

Cause of deathCommunicable/NoncommunicableNumber of deathsPercentage (%) of total deaths in 2019

Lower respiratory tract infectionsCommunicable774 2529.9
DiarrhoeaCommunicable496 2786.4
HIV/AIDSCommunicable434 5435.6
Ischaemic heart disease and strokeNoncommunicable429 1795.5
Parasitic diseasesCommunicable388 2295.0

Hypertension is the leading risk factor for ischaemic heart disease and stroke. Noncommunicable diseases rank fourth and are potentiated by hypertension.