Hypertension is a major public health problem affecting million of people worldwide; in the USA alone, over 45 million persons are hypertensives. This problem is likely to continue to increase as the population age. In fact after the age of seventy years, over 75% of women have high blood pressure, and this high prevalence among women might be explainable by the premature death of the hypertensive men. Among people with hypertension are those high-cardiovascular-risk populations. These include people with diabetes, heart failure, sleep apnea, metabolic syndrome, dyslipidemia, chronic kidney disease, previous stroke, and coronary heart disease.

In this special issue, we discuss the risk factors, pathophysiology, and management strategies in these high-risk populations, aiming to highlight the best evidence at hand from clinical research that provides guidance to the health care providers and informs policy makers as well on effective ways to deal with this rising epidemic. Potential topics include, but are not limited to:

• Hypertension in patients with diabetes and metabolic syndrome: pathophysiologic mechanisms and treatment strategies
• Hypertension among people with obstructive sleep apnea: implications of recent clinical data
• Cost-effective management in the hypertensive population: implication of the healthcare reform
• Management of hypertension in chronic kidney disease (CKD) population
• Resistant hypertension: pathophysiologic insights and treatment strategies
• Hypertension management in coronary heart disease patients: optimal goals and treatment options
• Hypertension management among heart failure patients

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijht/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: