Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation and Biomarkers in Cardiovascular Inflammation
1Harvard Medical School, Boston, MA, USA
2University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
3The University of Tokyo, Tokyo, Japan
4Brigham and Women's Hospital, Boston, MA, USA
Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation and Biomarkers in Cardiovascular Inflammation
Description
Westernized countries face a growing burden of cardiovascular diseases including acute complications of coronary atherosclerosis. Such diseases are often associated with diabetes mellitus, obesity, and chronic renal disease. Emerging clinical and experimental studies suggest that inflammation is central to the development of these cardiometabolic disorders. A proinflammatory subset of monocytes/macrophages and T lymphocytes may importantly contribute to pathological processes in cardiometabolic organs. Crosstalks between cardiometabolic organs may enhance systemic and local inflammatory milieu. In addition, accumulating evidence supports a key role for inflammation in the pathogenesis of vascular mineral deposition and calcific aortic valve stenosis. Thus, further understanding of the inflammatory nature of cardiovascular diseases and their association with metabolic disorders will lead to new therapeutic insights and aid in the prevention and management of the cardiometabolic syndrome and its complications.
We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the role of inflammation in cardiovascular diseases. We are particularly interested in articles describing the the proinflammatory signaling mechanisms participating in cardiovascular diseases; novel imaging modalities for characterization of vulnerable atherosclerotic plaques myocardial infarction, arterial and valvular calcification; new triggering mechanisms for inflammation; current concepts and future perspectives in the treatment of atherosclerosis and metabolic disorders. Potential topics include, but are not limited to:
- Role of inflammation in atherosclerosis, obesity, diabetes, chronic renal disease, and metabolic syndrome
- Identifying novel biomarkers of cardiovascular disease
- Cardiovascular inflammation and innate immunity
- Novel anti-inflammatory treatments of cardiovascular disease
- MicroRNA epigenetics in cardiovascular inflammation
- “Omics” in cardiovascular inflammation
- Crosstalks between remote organs in chronic or acute inflammation
- Novel signaling pathways in cardiovascular inflammation and ectopic calcification
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