Regulation of Expression of Oxacillin-Inducible Methionine Sulfoxide Reductases in Staphylococcus aureus

Figure 4

Regulation of msrA1/msrB locus in a methicillin-resistant S. aureus strain COL by SigB. The msrA1/msrB promoter-lacZ reporter strains were cultured in TSB and growth was measured as OD₆₀₀ (a). β-galactosidase activity levels were measured in S. aureus strain COL (open triangles) and its derivative sigB mutant (closed squares) during different stages of growth (b). Values indicate averages of data from at least three independent experiments ± standard error ( significant at ).

(a)

(b)