Research Article

Spectrum and the In Vitro Antifungal Susceptibility Pattern of Yeast Isolates in Ethiopian HIV Patients with Oropharyngeal Candidiasis

Table 5

In vitro antifungal susceptibility pattern of yeast isolates.

SpeciesPatternAntifungal drugs (, %)
AmCLFluKetoMicNY

C. albicans (106)S98 (92.4)105 (99.1)92 (86.8)95 (89.6)101 (95.3)105 (99.1)
I6 (5.7)0 (0)7 (6.6)5 (4.7)4 (3.8)1 (0.9)
R2 (1.9)1 (0.9)7 (6.6)6 (5.7)1 (0.9)0 (0)
C. glabrata (24)S21 (87.5)21 (87.5)19 (79.2)20 (83.3)19 (79.2)22 (91.6)
I1 (4.2)2 (8.3)1 (4.2)1 (4.2)5 (20.8)1 (4.2)
R2 (8.3)1 (4.2)4 (16.6)3 (12.5)0 (0)1 (4.2)
C. tropicalis (17)S9 (53.0)15 (88.2)10 (58.8)13 (76.5)11 (64.7)16 (94.1)
I5 (29.4)1 (5.9)1 (5.9)1 (5.9)6 (35.3)1 (5.9)
R3 (17.6)1 (5.9)6 (35.3)3 (17.6)0 (0)0 (0)
C. krusei (4)S0 (0)3 (75.0)0 (0)3 (75.0)0 (0)4 (100)
I3 (75.0)0 (0)2 (50)1 (25.0)4 (100)0 (0)
R1 (25.0)1 (25.0)2 (50)0 (0)0 (0)0 (0)
C. kefyr (2)S0 (0)2 (100)0 (0)1 (50)0 (0)1 (50)
I1 (50)0 (0)2 (100)1 (50)2 (100)0 (0)
R1 (50)0 (0)0 (0)0 (0)0 (0)1 (50)
C. laurentiiS1 (100)1 (100)1 (100)1 (100)1 (100)1 (100)
I0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
R0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
Rhodotorula spp.S1 (100)1 (100)1 (100)1 (100)1 (100)1 (100)
I0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
R0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)

All isolatesS130 (83.9)148 (95.5)123 (79.4)134 (86.5)133 (85.8)150 (96.8)
I16 (10.3)16 (10.3)13 (8.4)8 (5.2)21 (13.5)3 (1.9)
R9 (5.8)4 (2.6)19 (12.3)13 (8.4)1 (0.6)2 (1.3)

S: susceptible; I: intermediate; R: resistant; Am: amphotericin B; Clo: clotrimazole; Flu: fluconazole; Keto: ketoconazole; Mic: miconazole; NY: nystatin.