Engineering a Better Mousetrap: Can Microbes Target and Destroy Tumor Cells?
1Cancer Research Center, Columbia, USA
2Hammersmith Hospital, London, UK
3University of Missouri, Columbia, USA
4Nottingham University, Nottingham, UK
Engineering a Better Mousetrap: Can Microbes Target and Destroy Tumor Cells?
Description
This special issue is devoted to cancer therapeutics that utilize microbes (bacteria, bacteriophage, animal and plant viruses, or their components, either directly or as vehicles for cargo delivery of cancer therapeutics to their targets). Contributions are welcome from all over the world. We invite investigators to submit original research as well as review articles that will contribute to microbial targeting and destruction of tumors.
Potential topics include, but are not limited to:
- Tumor targeting via phage display
- Review of clinical phase 1 studies of microbial therapies
- Genetically engineered Salmonella as antitumor agent
- Quorum sensing techniques in studies of microbial therapies
- Clostridium as antitumor agent
- Bifidobacterium as antitumor agent
- Engineering of human viral genes (e.g., HIV) into vehicles for tumor targeting