Effects of Oral Sodium Bicarbonate Supplementation on Protein Metabolism and Inflammation in Iraqi Hemodialysis Patients: An Open-Label Randomized Controlled Trial

Table 1

Baseline characteristics of the study groups.

	Intervention group	Control group	value
Number	25	24
Age (years)	47.12 + 18.04	50.46 + 14.24	0.14
Gender (M/F)	10/15 (40%/60%)	12/12 (50%/50%)	0.33
Residence (urban/rural)	19/6 (76%/24%)	19/5 (79.2%/20.8%)	0.6
ESRD
Diabetes mellitus	9/36%	12/50%
Hypertension	2/8%	4/16.66%
Chronic glomerular disease	1/4%	2/8.33%
Cystic disease	3/12%	2/8.33%
Obstructive uropathy	1/4%	1/4.16%
Others	9/36%	3/12.5%
Dialysis vintage (years)	2.32 + 0.627	1.96 + 0.55	0.2
BMI	21.94 + 4.29	22.89 + 5.58	0.5
Weight (kg)	60.28 + 13.7	65 + 15.8	0.26
Systolic Bp (mm Hg)	133.72 + 23.4	149.58 + 31.5	0.05^∗
Diastolic Bp (mmHg)	81.3 + 12.5	85.29 + 15.4	0.32
Interdialytic weight gain	2.376 + 0.68	1.91 + 1	0.75
Arterial pH	7.26 ± 0.06	7.29 + 0.04	0.27
Serum bicarbonate (mmol/l)	17.57 ± 3.34	18.68 ± 3.29	0.98
Serum potassium (mEq/l)	5.64 ± 0.61	5.19 ± 0.72	0.45
Calcium (mg/dL)	8.25 + 2.2	8.18 + 1.4	0.19
Phosphate (mg/dL)	6.39 + 1.4	6.23 + 1.3	0.4
Alkaline phosphatase (U/L)	366 + 66	242 + 43	0.06
Vitamin D (ng/ml)	15.6 + 8.9	14.4 + 8.1	0.77
iPTH (pg/l)	654 + 115	430 + 58	0.02^∗
Kt/V	1.26 ± 0.33	1.23 ± 0.27	0.36
S. albumin (g/l)	4.11 ± 0.45	3.95 + 0.55	0.36
nPCR (g/kg per day)	0.90 ± 0.19	0.92 + 0.1	0.91
IL-6 (pg/ml)	16.22 ± 24.11	27.62 ± 47.51	0.179
Handgrip	38.8 ± 18.95	35.84 ± 15.39	0.25
Skinfold thickness (mm)	8.98 ± 5.53	10.92 ± 7.99	0.87