Effects of Oral Sodium Bicarbonate Supplementation on Protein Metabolism and Inflammation in Iraqi Hemodialysis Patients: An Open-Label Randomized Controlled Trial

Table 2

Clinical, laboratory, and nutritional data of the intervention and the control groups at three months of oral sodium bicarbonate therapy.

	Intervention	Control	value	95% CI
Weight (kg)	60.70 ± 13.88	65.19 ± 15.71	0.294	−13	4.02
Systolic Bp (mm Hg)	130.28 ± 22.57	145.63 ± 23.93	0.25	−28.7	−1.98
Diastolic Bp (mmHg)	78.64 ± 10.67	85.21 ± 15.00	0.083	−14	0.88
Interdialytic weight gain	2.42 ± 0.64	2.20 ± 1.14	0.405	−0.30	0.75
Arterial pH	7.34 ± 0.43	7.29 ± 0.07	0.008	0.11	0.75
S. bicarbonate (mmol/l)	20.69 ± 2.54	18.9 ± 3.85	0.047	0.17	3.5
S. sodium (mEq/l)	138.00 ± 3.11	133.59 ± 20.34	0.289	−3.86	12.6
S. potassium (mEq/l)	5.00 ± 0.43	5.33 ± 0.63	0.039	−0.63	−0.01
Calcium (mg/dL)	8.08 + 2.04	7.79 + 1.55	0.42	−0.74	1.32
Phosphate (mg/dL)	5.56 + 1.28	6.44 + 1.05	0.23	−1.56	−0.2
Alkaline phosphatase (U/L)	312 + 243	308 + 232	0.83	−132	140
Vitamin D (ng/ml)	21.72 + 5.9	11.89 + 6.1	0.06	0.9	18.7
iPTH (pg/l)	437 + 353	551 + 350	0.79	−316	88.4
S. albumin (g/l)	4.15 ± 0.49	3.79 ± 0.47	0.011	0.08	0.63
nPCR (g/kg/day)	1.06 + 0.27	0.90 + 0.27	0.033	−0.26	−0.01
IL-6 (pg/ml)	12.34 ± 10.62	22.88 ± 16.79	0.043	−18.68	−2.37
Kt/V	1.25 + 0.3	1.24 + 0.22	0.6	0.15	0.4
Handgrip	45.01 ± 19.19	33.93 ± 15.06	0.030	1.13	21.02
Skinfold thickness (mm)	10.26 ± 4.89	10.50 ± 7.97	0.899	−4.02	3.54