Synthesis and Characterization of New Thiolated Chitosan Nanoparticles Obtained by Ionic Gelation Method

Table 3

Thermodynamic profile of thiolated and native chitosan.

Sample	Gibbs energy ()	Enthalpy ()	Binding ()	Entropy ()	(active sites)
	calmol	calmol	M^−1	calK^−1mol^−1	Sites
Native Ch (Phase 1)	−8621.78	−7843	2.11 × 10^6	2.64	20
Native Ch (Phase 2)	−8527	1.70 × 10^4	1.8 × 10^6	88.7	35
Thiolated Ch (Phase 1)	−8938	−6750	3.6 × 10^6	7.41	13
Thiolated Ch (Phase 2)	−8852	1.79 × 10^4	3.11 × 10^6	86	23

Gibbs free energy, enthalpy change, and entropy.