Review Article

Identification of Myocardial Damage in Systemic Sclerosis: A Nuclear Cardiology Approach

Table 1

SSc subsets and organ involvements.

Diffuse cutaneous SScLimited cutaneous SSc

Skin sclerosisTruncal and acral skin involvementLimited to hands, feet, face, and forearms, or absent
Organ involvementEarly and significant incidence of interstitial lung disease, oliguric renal failure, diffuse gastrointestinal disease, and myocardial involvementSignificant late incidence of pulmonary hypertension, trigeminal neuralgia, calcinosis, and teleangiectasia
AntibodiesAnti-DNA topoisomerase I antibodiesAnticentromere antibodies