Research Article
Evaluation of Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis: A Single Center Experience
Table 2
SJIA patients classified with MAS according to the HLH-2004 diagnostic guidelines, MAS 2016 classification criteria, MS score, and/or ferritin/ESR ratio.
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aThe number in the parenthesis shows the number of fulfilled MAS criteria other than μg/L. It was not possible to evaluate the 2016 MAS criteria in six patients due to missing data on ferritin. bCalculation of the MS score: . Patients with a MS are typed in italics. MS score could not be calculated for thirteen SJIA patients due to missing data on ferritin and/or fibrinogen. cPatients with a ferritin: ESR ratio cut are typed in italics. Ferritin to erytrocyte sedimentation rate ratio could not be calculated for 6 patients due to missing data on both ferritin and ESR. dPatient diagnosed in 2015 developed subclinical MAS 42 days after onset of sJIA. eSensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) calculated against 2016 MAS classification criteria and expressed as percentage with 95% confidence interval in parenthesis. |