International Journal of Rheumatology / 2022 / Article / Tab 3 / Research Article
Autoimmune Idiopathic Inflammatory Myopathies: Pharmacological Differences and Similarities by Type of Myositis and by Sociodemographic Variables Table 3 Comparison of some sociodemographic and pharmacological variables between age groups of patients diagnosed with autoimmune idiopathic inflammatory myopathies in Colombia.
Variables <65 years ≥65 years % % Woman 334 69.4 142 74.7 0.173 Type of inflammatory myopathy — — — — — Overlap myositis 141 29.3 70 36.8 0.058 Polymyositis 136 28.3 62 32.6 0.265 Other dermatomyositis 112 23.3 33 17.4 0.093 Dermatopolymyositis 88 18.3 25 13.2 0.109 Juvenile dermatomyositis 4 0.8 0 0.0 0.582 Comorbidities 358 74.4 177 93.2 <0.001 Arterial hypertension 134 27.9 115 60.5 <0.001 Diabetes mellitus 67 13.9 72 37.9 <0.001 Hypothyroidism 65 13.5 59 31.1 <0.001 Rheumatoid arthritis 74 15.4 45 23.7 0.011 Chronic pain 49 10.2 28 14.7 0.096 Infections 107 22.2 50 26.3 0.262 Pharmacotherapy 440 91.5 174 91.6 0.966 Systemic glucocorticoids 381 79.2 146 76.8 0.501 Prednisolone 292 60.7 122 64.2 0.400 Prednisone 112 23.3 37 19.5 0.285 Dexamethasone 92 19.1 27 14.2 0.133 Methylprednisolone 40 8.3 12 6.3 0.383 Pulses 7 1.5 3 1.6 1.000 Deflazacort 34 7.1 13 6.8 0.918 Betamethasone 22 4.6 8 4.2 0.837 Hydrocortisone 7 1.5 3 1.6 1.000 Conventional DMARDs 346 71.9 151 79.5 0.045 Azathioprine 233 48.4 94 49.5 0.809 Methotrexate 166 34.5 76 40.0 0.182 Chloroquine 86 17.9 19 10.0 0.011 Hydroxychloroquine 25 5.2 7 3.7 0.407 Sulfasalazine 3 0.6 3 1.6 0.359 Leflunomide 4 0.8 1 0.5 1.000 Immunosuppressants 50 10.4 11 5.8 0.062 Mycophenolate 21 4.4 3 1.6 0.105 Cyclosporine 16 3.3 5 2.6 0.641 Cyclophosphamide 18 3.7 3 1.6 0.217 Human immunoglobulin 5 1.0 0 0.0 0.329 Biological DMARDs 21 4.4 4 2.1 0.256 Rituximab 17 3.5 4 2.1 0.462 Others ( ) ^ 4 0.8 0 0.0 0.582 Comedications — — — — — Analgesics 313 65.1 136 71.6 0.107 Antiulcer 287 59.7 126 66.3 0.111 Antihypertensives and diuretics 164 34.1 124 65.3 <0.001 Nonsteroidal anti-inflammatory drugs 215 44.7 68 35.8 0.035 Antihistamines 185 38.5 57 30.0 0.040
Fisher’s exact test. DMARD: disease-modifying antirheumatic drugs. ^Others: adalimumab, abatacept, belimumab, and certolizumab.