Incidence and Risk Factors of Thyroid Malignancy in Patients with Toxic Nodular Goiter

Table 1

Preoperative data.

Variable	Benign group; (n = 77)	Malignant group; (n = 21)	value
Age (year)	47.13 ± 11.94	48.67 ± 10.66	0.594
Gender
Male	12 (15.58%)	8 (38.1%)	0.023
Female	65 (84.42%)	13 (61.90%)
Comorbidities
Diabetes mellitus	9 (11.69%)	3 (14.29%)	0.748
Hypertension	9 (11.69%)	4 (19.05%)	0.378
Chronic liver disease	2 (2.6%)	0 (0%)	0.456
Family history of cancer thyroid	1 (1.3%)	0 (0%)	0.600
Preoperative diagnosis
TMNG	44 (57.14%)	17 (80.95%)	0.046
STN	33 (42.86%)	4 (19.05%)
Size of the dominant nodule (mm) by the US	32.29 ± 12.93	35.67 ± 14.43	0.303