High CD44 Immunoexpression Correlates with Poor Overall Survival: Assessing the Role of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma Patients from the High-Risk Population of Pakistan

Table 3

Patient characteristics (n = 100).

Characteristics	No.	Characteristics	No.
Gender		AJCC stage
Male	57	Stage I	19
Female	43	Stage II	32
Age division		Stage III	23
<40 years	18	Stage IV	26
40 and >40 years	82	Tonsil
Habits		Yes	2
Yes	79	No	98
No	21	Skin involvement
Habit pattern		Yes	3
Single	37	No	97
Multiple	42	Palate
Non-users	21	Yes	8
Tobacco/smoking		No	92
Yes	35	Mandible
No	65	Yes	26
Paan/supari		No	74
Yes	61	Retromandibular
No	39	Yes	16
Chalia/gutka/niswar		No	84
Yes	31	Floor of mouth
No	69	Yes	7
Primary tumour site		No	93
Cheek	63	Surgical margins
Tongue	37	Clear	62
Histological differentiation		Near	27
WDSSC	37	Involved	11
MDSCC	59	Radiotherapy
PDSCC	4	Yes	65
Size of primary tumour (T)		No	35
T1	21	Overall survival
T2	47	Alive	44
T3	15	Dead	56
T4	17	Recurrence
Lymph node metastasis (N)		Yes	74
N0	77	No	26
N1	13	SOX-2
N2	10	Positive	63
CD44		Negative	37
High	33	SOX-2 staining intensity
Low	67	Mild	32
CD133		Moderate	28
Positive	23	Strong	3
Negative	77	L1CAM
CD133 staining intensity		Positive	41
Mild	15	Negative	59
Moderate	6	L1CAM staining intensity
Strong	2	Mild	34
		Moderate	5
		Strong	2