Breast Cancer remains the most common malignant neoplasia among women worldwide. However, no other solid cancer has witnessed such a tremendous change and improvement in terms of diagnosis and management in the last 2 decades. Meanwhile, management of breast cancer has become increasingly complex, and this has shifted breast cancer treatment into a multidisciplinary science.

Earlier detection has resulted in a several-fold increased incidence of ductal carcinoma in situ (DCIS) in the last two decades, with a reported increase in diagnosis of 15% every year. DCIS represents now approximately 20–25% of newly diagnosed breast cancers, and it is, therefore, a major public health issue.

We invite investigators to contribute original research articles and review articles that will stimulate continuing efforts to ameliorate clinical management and outcome of ductal carcinoma in situ (DCIS). We are interested in articles which report findings relevant to management, including risk factors for local relapse, surgical approaches, use of radiation therapy, and chemopreventive agents. Articles which add to the understanding of the molecular mechanisms explaining the development of DCIS will be of particular relevance to this call. Potential topics include, but are not limited to:

• Diagnostic Imaging
• Molecular mechanisms of development
• Classification and pathologic risk factors
• Correlation between imaging and pathology
• Review of clinical trials
• Clinical management of DCIS
• Management of young women with DCIS
• Risk factors for local relapse
• Sentinel node biopsy in DCIS
• Radiation therapy for DCIS
• Chemoprevention

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