Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 17

Segmental arterial mediolysis reparative phase. The arrow points to foci of reparative granulation tissue undergoing early fibrosis (yellow stain) in the media and in the adventitia appearing as a crescent that partially encircles the artery. The latter putatively represents an antecedent to adventitial fibromuscular dysplasia. Movat stain ×100 (adapted with permission from Cardiovascular Pathology 18(6) copyright 2009, Elsevier Inc.).