Research Article
Development of an Antimicrobial Stewardship Intervention Using a Model of Actionable Feedback
Table 1
Parameters of antibiotic prescribing studied in audit and feedback intervention used in the neonatal intensive care unit.
| Stewardship concepts | Parameters |
| Inadequate coverage | (1) Empiric treatment of pathogen with ineffective antibiotic. | Appropriate diagnostic strategy | (2) Number of blood cultures obtained prior to initiation of empiric therapy for late-onset sepsis in infants with and without CVC. | Excessive antibiotics | (3) Days of treatment with broad-spectrum agent rather than narrower-spectrum agent based on pathogen susceptibilities. | | (4) Days of treatment with an agent for gram-negative pathogens following identification of a gram-positive pathogen or vice versa. | Antibiotic duration | (5) Duration of antibiotic treatment for culture-negative sepsis. | Antibiotic prophylaxis | (6) >2 antibiotic/day of perioperative antibiotics for cardiac surgery and >1 antibiotic/day for on-cardiac surgery. |
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