Research Article
Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil)
Table 2
Malaria symptoms occurring before and after drug treatment.
| Symptoms | | % | Before medication | After the start of medication | Value of |
| Gastrointestinal symptoms | | | | | | Nausea | 50 | 44% | 22% | 46% | 0.012 | Vomiting | 50 | 62% | 16% | 24% | 0.481 | Diarrhea | 50 | 72% | 4% | 26% | 0.003 | Pale stools | 50 | 88% | 0% | 12% | 0.031 | Loss of appetite | 50 | 44% | 32% | 46% | 0.143 | Mesogastric and/or hypogastric pain | 50 | 48% | 20% | 38% | 0.017 | Bitter taste in the mouth | 50 | 30% | 30% | 60% | 0.004 | Pain in hypochondria | 50 | 62% | 14% | 32% | 0.035 | Algic symptoms | | | | | | Headache | 49 | 14% | 76% | 70% | 0.581 | Myalgia | 50 | 58% | 30% | 22% | 0.454 | Arthralgia | 50 | 42% | 48% | 26% | 0.007 | Lower back pain | 50 | 40% | 52% | 32% | 0.031 | Retroocular pain | 50 | 60% | 36% | 18% | 0.022 | General symptoms | | | | | | Fever | 50 | 20% | 72% | 38% | 0.001 | Chills | 50 | 34% | 54% | 34% | 0.052 | Sweating | 50 | 36% | 54% | 40% | 0.143 | Weakness/malaise | 50 | 22% | 42% | 64% | 0.043 | Other symptoms | | | | | | Itching throat | 50 | 90% | 4% | 8% | 0.625 | Jaundice | 50 | 86% | 8% | 14% | 0.250 | Choluria | 50 | 36% | 20% | 56% | 0.001 | Dyspnea | 50 | 84% | 4% | 14% | 0.125 |
|
|
McNemar’s test.
|