Side Effects of Chloroquine and Primaquine and Symptom Reduction in Malaria Endemic Area (Mâncio Lima, Acre, Brazil)

Table 2

Malaria symptoms occurring before and after drug treatment.

Symptoms		%	Before medication	After the start of medication	Value of
Gastrointestinal symptoms
Nausea	50	44%	22%	46%	0.012
Vomiting	50	62%	16%	24%	0.481
Diarrhea	50	72%	4%	26%	0.003
Pale stools	50	88%	0%	12%	0.031
Loss of appetite	50	44%	32%	46%	0.143
Mesogastric and/or hypogastric pain	50	48%	20%	38%	0.017
Bitter taste in the mouth	50	30%	30%	60%	0.004
Pain in hypochondria	50	62%	14%	32%	0.035
Algic symptoms
Headache	49	14%	76%	70%	0.581
Myalgia	50	58%	30%	22%	0.454
Arthralgia	50	42%	48%	26%	0.007
Lower back pain	50	40%	52%	32%	0.031
Retroocular pain	50	60%	36%	18%	0.022
General symptoms
Fever	50	20%	72%	38%	0.001
Chills	50	34%	54%	34%	0.052
Sweating	50	36%	54%	40%	0.143
Weakness/malaise	50	22%	42%	64%	0.043
Other symptoms
Itching throat	50	90%	4%	8%	0.625
Jaundice	50	86%	8%	14%	0.250
Choluria	50	36%	20%	56%	0.001
Dyspnea	50	84%	4%	14%	0.125

McNemar’s test.