Mutations Associated with Rifampicin Resistance in Mycobacterium tuberculosis Isolates from Moroccan Patients: Systematic Review

Table 1

Characteristics of studies included in the review.

	Studies included in the review	Study area	Study population	No. of clinical MTB isolates	Year of collection	Sex ratio	Age range	Sample size
1	Oudghiri et al. 2018 [26]	Different cities in Morocco	Confirmed pulmonary TB	703	2010–2102	3.2	3–62 (80% were in the age group of 16–45 years old)	New: 228
								Previously treated (drug relapse and failure): 264
								Under treatment: 33
								Not available: 178
2	Karimi et al. 2018 [27]	Different cities located in the northern region	Suspected TB patients	70	2013-2014	5.36	16–72	New: 42
								Previously treated (drug relapse and failure): 14
								Unknown treatment history: 14
3	Ennassiri et al. 2017 [28]	Different cities in Morocco	Pulmonary TB	319	2013–2015	4.4	Median age of 35.6.	New: 88
								Previously treated: 231
4	Bentaleb et al. 2017 [29]	Different cities in Morocco	Confirmed pulmonary TB	67	NA	NA	NA	NA
5	Chaoui et al. 2014 [24]	Different cities in Morocco	Pulmonary TB	500	Isolates of MTB collected over a period of five years	NA	NA	NA
6	Zakham et al. 2013 [25]	Different cities in Morocco	Suspected TB patients	133	NA	2.64	15–80 (median age 38)	New: 100
								Previously treated (drug relapse or failure, chronic cases): 33

NA: not available, TB: tuberculosis, and MTB: Mycobacterium tuberculosis.