Development and Validation of Analytical Procedure for Elemental Impurities in Rosuvastatin Calcium Tablets by ICP-MS and Microwave Digestion

Table 5

Selection of elements’ isotopes.

Element	Isotopes abundance ratio	Potential interference	Selected
Cd	114Cd (28.73%)	114Cd: 40Ar + 74Ge, 12C + 102Ru, 16O + 98Mo	111Cd
	112Cd (24.13%)	112Cd: 40Ar + 72Ge, 14N + 98Mo, 16O + 96Mo
	111Cd (12.80%)
Pb	208Pb (52.40%)	None	208Pb
	206Pb (24.10%)
	207Pb (22.10%)
As	75As (100%)	None	75As
Hg	202Hg (29.80%)	None	202Hg
	200Hg (23.13%)
	199Hg (16.84%)
Co	59Co (100%)	None	59Co
V	51V (99.75%), 50V (0.25%)	None	51V
Ni	58Ni (68.27%)	58Ni: 58Fe, 40Ar + 18O	60Ni
	60Ni (26.10%)
	61Ni (1.13%)