Boldine Prevents Renal Alterations in Diabetic Rats
Figure 8
Boldine increases the relative Cx43 levels in mesangial cells grown in high glucose plus pro-inflammatory cytokines. Graph showing the relative levels of Cx43 under different conditions: normal glucose (white bar), high glucose + pro-inflammatory cytokines (TNF-α (10 ng/mL) and IL-1β (10 ng/mL)) (black bar), or high glucose + cytokines treated with 100 μM boldine (grey bar) for 24 h. Each bar represents the mean value ± SEM of 4 independent experiments. *, using the one-way ANOVA test followed by Bonferroni’s post hoc test.