Association between LXR-α and ABCA1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus in a Chinese Han Population

Table 1

Demographics and clinical characteristics of DM patients with and without kidney diseases.

Variables	DM ()^a	DKD ()^a
Age,	60.0 (53.0, 67.0)	62.5 (54.0, 71.0)	.003
Sex, male (%)	57.51 (199 (1)/346)	61.33 (184 (1)/300)	.336
BMI, kg/m^2	25.32 (23.08, 27.68)	25.80 (23.81, 28.18)	.021
Duration of diabetes, y	13.0 (10.0, 18.0)	15.0 (9.0, 20.0)	.149
History of hypertension (%)	51.16 (177/346)	78.0 (234/300)	<.001
SBP (mm Hg)	126.0 (120.0, 140.0)	140.0 (126.25, 150.0)	<.001
DBP (mm Hg)	80.0 (70.0, 80.25)	80.0 (74.0, 84.0)	.085
Scr (μmol/L)	62 (52.0, 72.15)	84.55 (64.93, 141.93)	<.001
TC (mmol/L)	4.16 (3.47, 4.88)	4.28 (3.50, 5.04)	.093
TG (mmol/L)	1.49 (1.03, 2.23)	1.70 (1.20, 2.58)	.011
LDL-C (mmol/L)	2.40 (1.93, 3.03)	2.42 (1.88, 2.96)	.898
HDL-C (mmol/L)	1.01 (0.83, 1.21)	0.96 (0.78, 1.17)	.427

indicates statistical significance. ^aData are shown as median (interquantile range) or %. Abbreviations: BMI: body mass index; DBP: diastolic blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; SBP: systolic blood pressure; TC: total cholesterol; TG: triglyceride.