Association between LXR-α and ABCA1 Gene Polymorphisms and the Risk of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus in a Chinese Han Population
Table 4
The combined effect of LXR-α rs7120118 and ABCA1 rs2230806 polymorphisms on DKD.
Genotypes
DM
DKD
Without adjustment
With adjustment¶
rs7120118
rs2230806
346
300
OR (95% CI)
OR (95% CI)
CC
AA
46
45
1#
—
1#
—
CC
AG
97
81
0.854 (0.515-1.461)
.540
0.882 (0.529-1.469)
.629
CC
GG
18
42
2.385 (1.198-4.747)
.013
2.531 (1.261-5.078)
.009
CT+TT
AA
40
33
0.843 (0.455-1.564)
.589
0.853 (0.456-1.595)
.619
CT+TT
AG
93
58
0.638 (0.377-1.079)
.093
0.641 (0.377-1.092)
.102
CT+TT
GG
52
41
0.806 (0.451-1.440)
.466
0.845 (0.470-1.520)
.574
.¶Adjustment for age and gender. #Reference category (odds ratio, 1.0). Abbreviations: DM: diabetes mellitus; DKD: diabetic kidney disease.
