Review Article

The Relationship between Erythrocytes and Diabetes Mellitus

Figure 1

Risk of erythrocytes in diabetic patients and its effects on cellular functions. The erythrocytes in diabetic patients face multiple risks, such as hyperglycemia, hyperosmolarity, oxidative stress, inflammation, and lipid metabolism disorder, which lead to increased aggregation, reduced cell deformability, and reduced membrane fluidity. These changes in erythrocytes eventually give rise to microcirculation disorder and diabetic complications.