Review Article
Current Studies on Molecular Mechanisms of Insulin Resistance
Table 1
Association with gene polymorphism of PC-1 (K121Q) with insulin resistance or T2D in various populations.
| Association with gene polymorphism of PC-1 (K121Q) | Population | Reference |
| Associated with T2D | Ukrainian | [36] | Associated with T2D | South African mixed-ancestry population | [38] | Associated with insulin resistance | North Indian | [37] | Associated with T2D susceptibility | Chinese | [39, 40] | Associated with T2D risk | American, European and African | [41] | Increased susceptibility to diabetic kidney disease | European and Asian | [42] | Enhanced susceptibility to coronary artery disease | South Indian patients with T2D | [50] | Associated with T2D | Zanjan | [43] | No association with T2D | Lebanese and Tunisian | [46] | No association with T2D or obesity | Chinese | [47, 48] | No association with insulin resistance in T2D | Pakistani Punjabi | [44] | No association with T2D | Malaysian | [45] | No association with insulin resistance or T2D | Danish Caucasians | [49] |
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