Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy

Figure 1

Differentially expressed genes between diabetic and normal samples. (a–d) The volcano plots indicate DEmRNAs, DEmiRNAs, DElncRNAs, and DEcircRNAs based on the fold and the adjusted value < 0.05. Red dots indicate upregulation genes, blue dots indicate downregulation genes, and gray dots represent other genes that are not differentially expressed. (e–h) The heatmap also describes DEmRNAs, DEmiRNAs, DElncRNAs, and DEcircRNAs between different groups. The color scale represents the relative expression levels of the DEGs, where red indicates higher expression and blue indicates lower expression. DEmRNAs: differentially expressed mRNAs; DEmiRNAs: differentially expressed microRNAs; DElncRNAs: differentially expressed long noncoding RNAs; DEcircRNAs: differentially expressed circular RNAs.

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