| Gene(s) | Changes in gene expression | Gene function | HIF dependency | References |
| cd80, cd83, cd86, hla II, and cd40 | ↑ | Costimulatory molecules | cd83: yes [30] cd40: yes [32] | [28–30, 32] | cx3cr1, ccr3, ccr2, and cxcr4 | ↑ | Chemokine receptors | | [29] | ccl13, ccl14, ccl18, ccl23, ccl24, and ccl26 | ↓ | Chemokines | | [29] | tnfsf14 | ↑ | Stimulation of T cells | | [29] | vegf | ↑ | Angiogenesis | Yes | [29] | il-8, mif | ↑ | Inflammatory cytokines |
il-8: dependency shown for human mesenchymal stem cells [39] mif: yes [40] | [29] | trem-1 | ↑ | IRS receptor, triggers release of inflammatory cytokines | Yes | [36, 37] | cxcl2, cxcl3, cxcl5, cxcl6, and cxcl8 | ↑ | Neutrophil recruitment | HRE found in cxcl2, cxcl5, and cxcl6 | [34] | ccl20, ccl3, and ccl5 | ↑ | Recruitment of activated T cells, monocytes, and immature DCs | HRE found in all of them | [34] | ccl18, ccl23 | ↓ | Chemoattractants for naïve/resting T cells | Most likely indirect | [34] | a2bar | ↑ | Adenosine receptor | Yes | [35] |
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