Research Article

Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma

Table 2

Interaction similarity scores of the selected HTL epitopes in CD70.

Protein nameEpitopeDRB1:0101 (PDB ID:4AH2)DRB1:0301 (PDB ID:2Q6W)DRB1:0401 (PDB ID:5LAX)DRB1:1101 (PDB ID:6CPL)DRB1:1501 (PDB ID:5V4M)DRB5:0101 (PDB ID:1FV)Average

CD70 (Homo sapiens)CD70 (54–72)122.22130.6130.66132.1129.6125.8128.49
CD70 (69–84)122.4138.8116.8113.6115.3113.6120.08

Higher rate shows better quality of peptide-MHC interactions.