Exosomes Derived from Schistosoma japonicum Cystatin-Treated Macrophages Attenuated CLP-Induced Sepsis in Mice

Figure 5

Treatment with Sj-Cys-EXO reduced liver, kidney, and lung tissue damage caused by CLP-induced sepsis. (a) The representative histopathology results of liver, kidney, and lung stained with H&E from mice 12 hr after CLP or sham surgery treated with Sj-Cys-EXO, EXO, or PBS. (b) The pathological score in liver, lung, and kidney from different groups of mice. The magnification ×200, scale bar = 100 µm. For (b), n = 5 per group. The results are presented as mean ± SD. , , .

(a)

(b)