Disturbances in the IgG Antibody Profile in HIV-Exposed Uninfected Infants Associated with Maternal Factors
Table 1
Demographic characteristics of HIV-unexposed uninfected (HUU) or HIV-exposed uninfected (HEU) newborns and their corresponding mothers.
Control mothers
HIV+ mothers
p Values
Maternal age (years, mean ± SD)
31.4 (5.3)
26.7 (6.1)
0.0028#
Percentages of Th cells (mean ± SD)
45.46 (6.4)
29.4 (13.8)
<0.0001#
CD4 count (cells/mm3, mean ± SD)
n/a
1,061 (377.8)
n/a
Viral load (copies/mL: n (%))
n/a
6,954 (3643.9)
n/a
HUU newborns
HEU newborns
p Values
Gestational age (weeks, mean ± SD)
38.3 (1.3)
37.8 (1.7)
0.0533#
Length at birth (cm, mean ± SD)
48.4 (2.2)
48.2 (2.2)
0.5160#
Birth weight (g, mean ± SD)
2,979 (374.9)
2,815 (420.1)
0.0619#
Cephalic perimeter (cm, mean ± SD)
34.3 (1.3)
33.6 (1.5)
0.0423#
Delivery type
N = 4, C = 67
N = 17, C = 52
<0.0001##
Gender
F = 36 M = 35
F = 35 M = 34
0.9973##
Percentages of Th cellsπ (mean ± SD)
66.01 (8.7)
65.9 (11.8)
0.9429##
CD4 count (cells/mm3, mean ± SD)
n/a
2,214 (943.3)
n/a
The results are shown as the mean and standard deviation. π refers to the percentage of Th cells among T cells. p Values for differences between groups were calculated using an unpaired t-test (#) or chi-square test (##). Bold values represent statistically significant results. n/a, not applicable.