Age- and Diet-Dependent Changes in Hepatic Lipidomic Profiles of Phospholipids in Male Mice: Age Acceleration in Cyp2b-Null Mice

Figure 8

Lipid species and measured variables associated with differences between Cyp2b-null and WT mice. (a) Random forest analysis of key lipids predictive of differences between Cyp2b-null and WT mice. (b) Principal component analysis (PCA) biplot showing relationships between treatment groups and measured variables such as physiological parameters, serum lipids, and phospholipid species. Variables include serum lipids, WAT somatic index (WSI), body weight, and lipid species in order to associate specific biochemical parameters with different treatment groups (diet and age) and genotypes (WT and Cyp2b-null).

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